Selected Publications

Havrylov, S. and M. Park (2014). “MS/MS-based strategies for proteomic profiling of invasive cell structures.” Proteomics.

Tofigh A, Suderman M, Paquet ER, Livingstone J, Bertos N, Saleh SM, Zhao H, Souleimanova M, Cory S, Lesurf R, Shahalizadeh S, Garcia Lopez N, Riazalhosseini Y, Omeroglu A, Ursini-Siegel J, Park M, Dumeaux V, Hallett M. (2014). “The prognostic ease and difficulty of invasive breast carcinoma.” Cell Rep 9(1): 129-142.

Vadnais C, Shooshtarizadeh P, Rajarudai CV, Lesurf R, Hulea L, Davoudi S, Cadieux C, Hallett M, Park M, Nepveu A. (2014). “Autocrine Activation of the Wnt/beta-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers.” Biol Open 3(10): 937-946.

Hudson J, Ha JR, Sabourin V, Ahn R, La Selva R, Livingstone J, Podmore L, Knight J, Forrest L, Beauchemin N, Hallett M, Park M, Ursini-Siegel J. (2014). “p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.” Mol Cell Biol 34(19): 3689-3701.

Lai, AZ, Cory S, Zhao H, Gigoux M, Monast A, Guiot MC, Huang S, Tofigh A, Thompson C, Naujokas M, Marcus VA, Bertos N, Sehat B, Perera RM, Bell ES, Page BD, Gunning PT, Ferri LE, Hallett M, Park M. (2014). “Dynamic reprogramming of signaling upon met inhibition reveals a mechanism of drug resistance in gastric cancer.” Sci Signal 7(322): ra38.

Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, Park M, Leone G. (2013). “Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.” PLoS One 8(8): e71533.

Ahn R, Sabourin V, Ha JR, Cory S, Maric G, Im YK, Hardy WR, Zhao H, Park M, Hallett M, Siegel PM, Pawson T, Ursini-Siegel J. (2013). “The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression.” Cancer Res 73(14): 4521-4532.

Laurin M, Huber J, Pelletier A, Houalla T, Park M, Fukui Y, Haibe-Kains B, Muller WJ, Côté JF. (2013). “Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis.” Proc Natl Acad Sci U S A 110(18): 7434-7439.

Ursini-Siegel J, Park M. (2013). “It takes two to tango in the microenvironment!” Breast Cancer Res 15(2): 102.

Knight JF, Lesurf R , Zhao H , Pinnaduwage D , Davis RR , Saleh SM , Zuo D , Naujokas MA , Chughtai N , Herschkowitz JI , Prat A , Mulligan AM , Muller WJ , Cardiff RD , Gregg JP , Andrulis IL , Hallett MT , Park M.(2013). “Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer.” Proc Natl Acad Sci U S A 110(14): E1301-1310.

Bell ES,. Park M. (2012). “Models of crk adaptor proteins in cancer.” Genes Cancer 3(5-6): 341-352.

Mourskaia  AA, Amir E, Dong Z, Tiedemann K, Cory S, Omeroglu A, Bertos N, Ouellet V, Clemons M, Scheffer GL, Park M, Hallett M, Komarova SV, Siegel PMl. (2012). “ABCC5 supports osteoclast formation and promotes breast cancer metastasis to bone.” Breast Cancer Res 14(6): R149.

Pepin F, Bertos N, Laferrière J, Sadekova S, Souleimanova M, Zhao H, Finak G, Meterissian S, Hallett MT, Park M.(2012). “Gene-expression profiling of microdissected breast cancer microvasculature identifies distinct tumor vascular subtypes.” Breast Cancer Res 14(4): R120.

Lu KV, Chang JP, Parachoniak CA, Pandika MM, Aghi MK, Meyronet D, Isachenko N, Fouse SD, Phillips JJ, Cheresh DA, Park M, Bergers G. (2012). “VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex.” Cancer Cell 22(1): 21-35.

Fathers KE , Bell, ES, Rajadurai CV, Cory S, Zhao H, Mourskaia A, Zuo D, Madore J, Monast A, Mes-Masson AM, Grosset AA, Gaboury L, Hallett M, Siegel P, Park M.(2012). “Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.” Breast Cancer Res 14(3): R74.

Garbe JC, Pepin F, Pelissier FA, Sputova K, Fridriksdottir AJ, Guo DE, Villadsen R, Park M, Petersen OW, Borowsky AD, Stampfer MR, Labarge MA. (2012). “Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.” Cancer Res 72(14): 3687-3701.

Wang, Y, Roche O, Xu C, Moriyama EH, Heir P, Chung J, Roos FC, Chen Y, Finak G, Milosevic M, Wilson BC, The BT, Park M, Irwin MS, Ohh M. (2012). “Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1.” Proc Natl Acad Sci U S A 109(13): 4892-4897.

Parachoniak  CA, Park M. (2012). “Dynamics of receptor trafficking in tumorigenicity.” Trends Cell Biol 22(5): 231-240.

Rajadurai CV, Havrylov S, Zaoui K, Vaillancourt R, Stuible M, Naujokas M, Zuo D, Tremblay ML, Park M. (2012). “Met receptor tyrosine kinase signals through a cortactin-Gab1 scaffold complex, to mediate invadopodia.” J Cell Sci 125(Pt 12): 2940-2953.

Lai AZ, Durrant M, Zuo D, Ratcliffe CD, Park M. (2012). “Met kinase-dependent loss of the E3 ligase Cbl in gastric cancer.” J Biol Chem 287(11): 8048-8059.

 

 

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